The Impacts of Type 2 Diabetes Mellitus on Bone Markers in the Elderly Thai Women
Phasook Pooruk MD*, Nipat Kittimanon MD*, Pilanthana Janthorn BNS*, Narong Bunyaratavej MD**
Affiliation : * Department of Family Medicine, Buddhachinaraj Hospital, Phitsanulok, Thailand ** Department of Orthopaedic Surgery, Siriraj Hospital, Mahidol University, Bangkok, Thailand
A comparison study of bone turnover between the diabetic type 2 and the non-diabetic patients was conducted by using the age matching technique. The bone markers of the diabetic type 2 patients showed CTx = 0.48 ng/ml, NMID osteocalcin = 24.62 ng/ml and PINP = 38.61 ng/ml. All study parameters of bone markers were higher than the control group. Thus, the diabetic cases with high bone turnover assuredly predisposed to osteoporosis. The bone change consistently monitored particularly in the diabetic cases could prevent osteoporosis. The high calcium diets and regular exercises were recommended for the diabetic patients.
Keywords : Bone Markers, Diabetes mellitus type 2, Elderly
