Validity and Reliability of the Thai Mini Asthma Quality of Life Questionnaire
Sunee Lertsinudom BCP*, Nutjaree Pratheepawanit Johns PhD*, Suthan Chanthawong GradDiplo*, Watchara Boonsawat MD, PhD**, Chanee Samosorn MSc***
Affiliation : * Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand ** Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand *** Pharmacy, Srinagarind Hospital, Khon Kaen, Thailand
Objective : The present study assessed the validity and reliability of the Thai Mini AQLQ in the Easy Asthma
Clinic, Srinagarind Hospital.
Material and Method: The present study used a cross sectional design, using an interview method by two
trained-interviewers. The Thai Mini AQLQ consists of 15 items categorized into Symptoms, Activities, Emotions,
Environment and Overall Scores. Scores range from 0 to 7 with higher scores meaning better quality of life.
Cronbach’s alpha was used to test for internal consistency reliability. Known group validation regarding
asthma control was analyzed by the t-test and multiple regression, adjusting for age, gender and education.
Results : Of 168 patients recruited, 113 were controlled and, of these 55 were uncontrolled asthma patients,
with an average age 53 + 13 years. Patients with controlled asthma reported significantly better scores in all
domains compared with uncontrolled asthma: symptoms 6.6 + 0.54 vs. 4.7 + 1.14, p < 0.001; Activity 6.7 +
0.57 vs. 5.0 + 1.36, p < 0.001; emotion 6.4 + 0.91 vs. 4.6 + 1.67, p < 0.001; environment 5.3 + 1.10 vs. 4.1 +
1.24, p < 0.001 and overall scores 6.3 + 0.51 vs. 4.6 + 0.96, p < 0.001. Adjusting for age, gender and education
using multiple regression, there was also a significant difference in all domains of Thai MiniAQLQ between
the controlled and uncontrolled asthma patients. Internal consistency reliability was within the acceptable
range (> 0.7) for all domains, except environment (overall 0.910; symptoms 0.855; activities 0.886; emotions
0.765 and environment 0.616).
Conclusions: Thai Mini AQLQ has known to be reliable and valid. Further study on test-retest reliability and
responsiveness to change are warranted.
Keywords : Quality of life, Asthma, Thai MiniAQLQ, Routine care
