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Agranulocytosis in Dengue Hemorrhagic Fever: A Neglected Condition

Somchai Insiripong MD*

Affiliation : * Department of Medicine, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand

A granulocytosis in dengue hemorrhagic fever has not been mentioned, it may probably be included under the term of leucopenia. Here is the case of a 14-year Thai boy presenting with fever and diarrhea for 3 days. He was diagnosed as dengue hemorrhagic fever, grade I because he had hemoconcentration, thrombocytopenia without bleeding and positive IgM dengue antibody. On the 5th day, he developed agranulocytosis and was treated with G-CSF and empirical antibiotics. His leucocyte count was successfully normalized within 1 day and persistently sustained until discharge.

Keywords : Agranulocytosis, Dengue Hemorrhagic Fever


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