Thailand Diabetic Registry Cohort: Predicting Death in Thai Diabetic Patients and Causes of Death
Thongchai Pratipanawatr MD*, Petch Rawdaree MD**, Thanya Chetthakul MD***, Pongamorn Bunnag MD***, Chardpraorn Ngarmukos MD***, Yupin Benjasuratwong MD****, Rattana Leelawatana MD*****, Natapong Kosachunhanun MD******, Nattachet Plengvidhya MD*******, Chaicharn Deerochanawong MD********, Sompongse Suwanwalaikorn MD*********, Sirinate Krittiyawong MD********** Sirima Mongkolsomlit BSc**********, Chulaluk Komoltri PhD***********
Affiliation : * Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand ** Department of Medicine, Bangkok Metropolitan Medical College and Vajira Hospital, Bangkok, Thailand *** Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand **** Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand ***** Department of Medicine, Prince of Songkla University, Songkhla, Thailand ****** Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand ******* Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand ******** Department of Medicine, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand ********* Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand ********** Theptarin General Hospital, Bangkok, Thailand *********** Faculty of Public Health, Thumasart University, Phatumthani, Thailand *********** Division of Research and Development, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
Introduction: The prevalence of type 2 diabetes in Thailand is 9.8 percent which is double the number forecast by World
Health Organization. There is inadequate information to statistically represent all Thai diabetic patients for their causes of
death.
Objective : To determine the clinical characteristics that predicted death and causes of death in Thai diabetic patients.
Material and Method: This prospective cohort was a 3-year follow-up study of the Thai Diabetes Registry project done
between April, 2003, and February, 2006, which registered 9,419 diabetic patients attending 11 diabetic clinics in tertiary
medical centers in Bangkok and major provinces of Thailand. The dead or alive status (99.5%) was determined. The causes
of death were defined by reviewing the medical records.
Results : Of the 9,370 diabetic patients registered, 425 patients died, 1.84 percent per year. There was an increased risk of
death associated with age, type of healthcare plan, lower education, insulin use, smoking, history of coronary artery disease
and cerebrovascular disease, serum creatinine and high HbA1c. Lipid-lowering medication and metformin decreased the risk
of death. Cardiovascular disease, infection and cancer were the prevalent causes of death.
Conclusion : The present study showed risk factors that influenced death and causes of death in Thai diabetics.
Keywords : Death rate, Diabetes mellitus, Risk factors of death, Causes of Death.
