Prevalence of High-Grade Cervical Intraepithelial Neoplasia (CIN) in the Patients with Atypical Squamous Cells of Undetermined Significance (ASC-US) Pap Smears: Hospital Based, Dynamic Population Area
Anusorn Panyanupap MD*, Yuthadej Thaweekul MD*, Yenrudee Poomtavorn MD*, Karicha Mairaing MD*, Komsun Suwannarurk MD*, Junya Pattaraarchachai MD**, Kronkarn Bhamarapravatana MD***
Affiliation : * Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand ** Department of Community Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand *** Department of Preclinical Science, Faculty of Medicine, Thammasat University, Pathumthani, Thailand
Objective : To determine the prevalence of cervical intraepithelial neoplasia (CIN) 2-3 (high-grade CIN) among women with
Atypical Squamous Cells of Undetermined Significance (ASC-US) Pap smear.
Material and Method: A retrospective medical record review of 220 women with ASC-US cervical Pap smear, including age,
menstruation status, parity, placed of residence, occupation, main complaint, and definite histopathological result between
July 2007 and January 2010 was done.
Results : The prevalence of high-grade CIN 2 and CIN 3 in Thammasat University Hospital were 8.6% and 3.2% respectively.
No cancer was found in the present study. There was no statistically significant difference in the prevalence of high-grade CIN
between the patients who were 50 years old or more and those who were younger.
Conclusion : Prevalence of high-grade CIN in women with ASC-US was 11.8%. Immediate colposcopy is recommended in
women with ASC-US.
Keywords : Pap smear, ASC-US, High grade CIN
