The Efficacy of Silver Mesh Dressing Compared with Silver Sulfadiazine Cream for the Treatment of Pressure Ulcers
Apirag Chuangsuwanich MD*, Orawan Charnsanti MD**, Visanu Lohsiriwat MD*, Chupaporn Kangwanpoom RN*, Narumol Thong-In PN*
Affiliation : * Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ** Faculty of Medicine, Songklanakrarin Hospital, Prince of Songkla University, Songkhla, Thailand
Background : Controlling infection and promoting healing should be aims of pressure ulcer treatment along with improving
a patient’s general condition and relieving pressure. Many pressure ulcers present with cavities, tracks or a combination of
these. A new silver mesh dressing (TegadermTM Ag Mesh dressing) has the ability to contour around and conform to irregular
surfaces of a wound bed.
Objective : To evaluate the efficacy of a silver mesh dressing compared with silver sulfadiazine cream for pressure ulcer
treatment.
Material and Method: A prospective, randomized, clinical trial was conducted in patients with pressure ulcers grade III or
IV. The patients were divided randomly by computer into two 20 patient-groups. The study period was eight weeks for each
patient. Demographic data, wound size, wound photography, and bacterial wound culture were recorded at the beginning of
the study and every two weeks thereafter. Wound beds were covered with silver sulfadiazine cream in the control group and
silver mesh dressing in the experimental group. Dressings were changed twice a day in the control group and every three days
in the experimental group.
Results : Forty-five patients enrolled in the present study but only 40 patients finished the study. Twenty patients in each group
finished the eight-week study. The mean healing rates and the percentage of reduction in PUSH score at eight-week were better
in the study group than in the control group but they were not statistically significant. Better changing in bacteriological study
after the treatment was shown in both groups. The estimated average cost of the treatment in the mesh group was 263 USD
per patient while it was 1812 USD in the cream one (p = 0.0001). Silver mesh dressing can be adapted very well on the bed,
can control infection, and promote wound healing. Wound reduction was greater in the experimental group than the control
group. The cost of treatment, using silver mesh was cheaper than using silver sulfadiazine cream significantly.
Conclusion : Silver mesh dressings is one of the choices for pressure ulcer treatment with good healing rate, minimal care
and lower overall cost.
Keywords : Silver dressing, Pressure ulcer, Wound
