I-131-Avid Renal Metastasis from Hurthle Cell Follicular Carcinoma: A Case Report with Literature Review
Anchisa Kunawudhi MD1, Sirachat Vidhyarkorn MD2, Chetsadaporn Promteangtrong MD1, Chanisa Chotipanich MD1
Affiliation : 1 Nuclear Medicine Division, Chulabhorn Hospital and National Cyclotron and PET Centre, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, Thailand 2 Diagnostic and Interventional Radiology Department, Chulabhorn Hospital, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, Thailand
Renal metastasis from thyroid cancer is uncommon, and computed tomography and magnetic resonance imaging findings cannot clearly differentiate renal metastases from renal cell carcinoma. However, I-131 total body scans almost always reveal radioiodine avidity in metastatic renal lesions from thyroid cancer but not in renal cell carcinoma. Hence, I-131 total body scans can be used for diagnosis and treatment planning in this rare patient population. These findings were reported mostly from the follicular variant of papillary thyroid cancer and follicular thyroid cancer. This report presents a case of renal metastasis from Hurthle cell follicular carcinoma with a literature review. The previous report on treatment options in well-differentiated renal thyroid cancer metastases included nephrectomy and radioiodine treatment. Patients with renal metastases typically also had other distant metastases and thus had poor prognoses and treatment outcomes.
Keywords : Renal metastasis, Hurthle cell carcinoma, Follicular carcinoma, Thyroid cancer, Total body scan, MRI, CT
