Outcomes of Complete Radical Hysterectomy in Early-Stage Cervical Cancer Patients with Intra-Operative Detection of Nodal Metastases
Suphet Tuipae MD*, Chayada Wongsuwan MD**
Affiliation : * Department of Obstetrics and Gynecology, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand ** Department of Obstetrics and Gynecology, Rajavithi Hospital, Bangkok, Thailand
Objective : To determine the overall 5-year survival rate and treatment-related complications in stage IB-IIA cervical cancer
patients with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy and systematic
lymphadenectomy.
Material and Method: The medical records of FIGO stage IB-IIA cervical cancer patients who underwent radical hysterectomy
and pelvic lymphadenectomy in Rajavithi Hospital between January 1985 and December 2006 were retrospectively reviewed.
Of the 247 node-positive stage IB-IIA cervical cancer patients, 121 patients displayed evidence of intra-operative detection
and underwent complete radical hysterectomy with systematic lymphadenectomy. These 121 patients were reviewed of which
107 were in stage IB and 14 were in stage IIA. Overall 5-year survival rate and treatment-related complications were
investigated.
Results : The median follow-up period was 117 months (range 60-312 months). Of the 121 stage IB-IIA cervical cancer
patients with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy and pelvic
lymphadenectomy, the overall 5-year survival rate was 70.5%. The major treatment-related complications were intra-
operative hemorrhage and post-operative bladder atony which accounted for 43.0% and 10.7%, respectively.
Conclusion : Early-stage cervical cancer patients with intra-operative detection of pelvic node metastases who underwent
complete radical hysterectomy had favorable survival outcomes and manageable complications.
Keywords : Cervical cancer, Radical hysterectomy, Pelvic lymph node metastases, Intra-operative detection, Survival, Complication
