Treatment of 4-5 year old patients with Cleft Lip and Cleft palate in Tawanchai Center: Prevalence and Type of Associated Malformations
Suteera Pradubwong MSN*, Sumalee Pongpagatip MA*, Pornpen Pathumwiwatana BSc*, Pakaphan Kiatchoosakun MD**, Manat Panamonta MD**, Bowornsilp Chowchuen MD***
Affiliation : * Division of Nursing, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand ** Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand *** Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Background : Patients with cleft lip/palate may have other associated malformations but the reported prevalence and type of
associated malformations varied between different studies.
Objective : To report the prevalence and the type of associated malformations in Northeastern Thai patients with cleft lip/
palate.
Material and Method: A retrospective study of 123 cleft lip/palate patients aged 4-5 years was carried out at the Tawanchai
Cleft Center, Khon Kaen University during the period from October to December 2011. Data were collected by reviewing the
patient’s medical records.
Results : Seventeen (14%) of the 123 patients had associated malformations. Four (21%) of the 19 patients with cleft palate,
eleven (15%) of the 74 patients with clefts lip and palate, and two (7%) of the 30 patients with cleft lip had associated
malformations. The organ systems affected by associated malformations were cardiovascular system (41%), craniofacial
anomaly (23%), skeletal system (12%), urogenital system (12%) and central nervous system (12%). Atrial septal defect and
tetralogy of Fallot were most common associated cardiovascular malformation found.
Conclusion : The high prevalence of associated malformations found in patients with cleft lip/palate emphasizes the need for
a thorough screening of associated malformations and congenital heart disease of all cleft lip/palate patients.
Keywords : Cleft lip, Cleft palate, Associated malformations, Congenital heart disease
