Subcutaneous Zygomycosis in Children: 2 Case Reports
Nootchanard Mahamaytakit MD*, Srisupalak Singalavanija MD*, Wanida Limpongsanurak MD*
Affiliation : * Dermatology Unit, Queen Sirikit National Institute of Child Health, College of Medicine, Rungsit University, Bangkok, Thailand
Basidiobolus ranarum is an uncommon subcutaneous zygomycosis mostly found in immunocompetent children in tropical countries. Presence of slow growing non-tender, non-inflammatory, subcutaneous swelling that does not spread beyond the subcutaneous tissue are classic clinical features. The authors report two cases of subcutaneous zygomycosis which tissue cultures were positive for Basidiobolus ranarum. The first case was a 10-months-old boy presented with prolonged high fever and a rapidly expanding ulcerated plaque unresponsive to systemic antibiotic. The second case was a 2-years-old girl presented with slow expanding mass at the buttock. Histopathology of both cases showed lobular panniculitis with eosinophilic infiltration and fungal culture revealed Basidiobolus ranarum. Oral itraconazole was given with good clinical response in both cases.
Keywords : Subcutaneous zygomycosis, Basidiobolus ranarum, Children
