Metabolic Syndrome in Obese Thai Children: Defined Using Modified ‘The National Cholesterol Education Program/Adult Treatment Panel III’ Criteria
Sanguansak Rerksuppaphol MD*, Lakkana Rerksuppaphol MD**
Affiliation : * Department of Pediatrics, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand ** Department of Preventive Medicine, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand
Background : Obesity is considered to be a risk of metabolic syndrome; however, data on the prevalence of metabolic
syndrome in Thai obese children are scarce.
Objective : The present study aims to determine the prevalence of metabolic syndrome in Thai obese children.
Material and Method: A cross-sectional study was conducted on 113 obese children who were students of a public elementary
school in Ongkharak district, Thailand, in 2013. Anthropometric data, blood pressure and biochemical parameters were
measured. Metabolic syndrome was defined using modified ‘the National Cholesterol Education Program/Adult Treatment
Panel III (NCEP/ATPIII)’ criteria.
Results : The prevalence of metabolic syndrome in obese children was 50.4%. Children with metabolic syndrome had
significantly higher waist circumference (86.9 vs. 82.4 cm, p-value = 0.049), biceps skinfold thickness (17.2 vs. 14.9 mm,
p-value = 0.017), suprailiac skinfold thickness (36.5 vs. 31.8 mm, p-value = 0.019), systolic blood pressure (119.7 vs. 112.6
mmHg, p-value = 0.007), diastolic blood pressure (73.7 vs. 69.0 mmHg, p-value = 0.022), fasting blood glucose (97.4 vs.
93.6 mg/dL, p-value = 0.009) and triglyceride levels (140.0 vs. 85.6 mg/dL, p-value <0.001) than those without metabolic
syndrome. HDL-cholesterol was significantly lower in children with metabolic syndrome than those in without metabolic
syndrome (48.7 vs. 63.1 mg/dL, p-value <0.001).
Conclusion : Of the sample, approximately half of children with obesity had metabolic syndrome. The prevalence of metabolic
syndrome appears to be on the increase. Strategies for childhood obesity and metabolic syndrome prevention are urgently
needed for Thai children.
Keywords : Child, Cholesterol, Metabolic Syndrome, Obesity, Triglycerides
