Antibacterial Activity of Excretions-Secretions from Chrysomya megacephala Against Escherichia coli
Tarinee Chaiwong PhD*, Thunyakarn Srivoramas MSc*, Plalakorn Sebsumran MSc*, Marutpong Panya PhD*, Surasak Wanram PhD*, Pawana Panomket PhD*
Affiliation : * College of Medicine and Public Health, Ubon Ratchathani University, Ubon Ratchathani, Thailand
Background : The blowfly, Chrysomya megacephala, is distributed worldwide. Previous studies found maggot excretions-
secretions from other blowfly species inhibited pro-inflammatory response and antimicrobial activity.
Objective : This study aimed to test the bactericidal activity of excretions-secretions from C. megacephala larvae.
Material and Method: A total of 1,500 3-day-old larvae were used to collect excretions-secretions (ES) modified by the
Barnes method. The bactericidal activity of the excretions-secretions was test by Pseudomonas aeruginosa, Staphylococcus
aureus, and Escherichia coli using suitable liquid culture assay. Scanning electron microscope (SEM) was used to investigate
the morphological change of the bacteria.
Results : E. coli were significantly inhibited by excretions-secretions from C. megacephala larvae. P. aeruginosa and S. aureus
were not found to inhibit growth.
Conclusion : The excretions-secretions from C. megacephala larvae may have a medical property for the inhibition of
bacterial growth.
Keywords : Chrysomya megacephala, Excretions-secretions, Antimicrobial
