Treatment Modalities and Outcomes of Infantile Hemangiomas at Srinagarind Hospital
Leelawadee Techasatian MD*, Nopphanan Phukam MD**
Affiliation : * Division of Dermatology, Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand ** Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Background : There are many treatment modalities for infantile hemangiomas. During the past decades, systemic corticosteroid
was the mainstay therapy in this condition. However, the most recent option of using oral propranolol has been considered
as a first line therapy instead of systemic corticosteroid. On the other hand, there are still many treatment modalities which can
be used as an alternative option in treating this condition.
Objective : To explore the epidemiology of infantile hemangiomas, treatment modalities and outcomes at Srinagarind Hospital
during 2004-2014.
Material and Method: Retrospective chart reviewed from the out patient clinic’s database at Srinagarind Hospital, Faculty
of Medicine, Khon Kaen University, Thailand.
Results : There were a total of 154 infantile hemangiomas. Female to male ratio was 1.8:1. The most common locations of
infantile hemangiomas were head and neck areas (69.0%), followed by extremities (21.0%) and trunk (10.0%). Treatment
modalities for infantile hemangiomas during the past 10 years (based on initial approaches) were oral propranolol (57.1%),
oral prednisolone (17.5%), surgery (10.4%), interferon alpha (9.8%), vincristine (4.5%) and laser (0.6%). All treatment
modalities showed high efficacy in treating this condition.
Conclusion : There are many effective treatment modalities for infantile hemangiomas. Even though oral propranolol has
become the first line therapy in this condition, other treatment options are still effective and useful, especially with those
unresponsive to oral propranolol.
Keywords : Infantile hemangiomas, Treatment modality, Treatment outcome, Oral propranolol
