A Multi-center Thai University-based Surgical Intensive Care Unit Study (THAI-SICU Study): Incidence of Acute Myocardial Infarction and Associated Factors
Waraporn Chau-In MD*1, Sarinya Chanthawong MD*1, Tanyong Pipanmekaporn MD, PhD*2, Suneerat Kongsayreepong MD*3, Kaweesak Chittawatanarat MD, PhD*4, Nonthida Rojanapithayakorn MD*1, the THAI-SICU study group
Affiliation : *1 Department of Anesthesiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand *2 Department of Anesthesiology, Faculty of Medicne, Chiang Mai University, Chiang Mai, Thailand *3 Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand *4 Departmento of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Introduction: To describe the incidence, characteristics and outcomes of acute myocardial infarction (AMI) and determine
risk factor(s) of AMI in THAI-surgical intensive care unit (SICU).
Material and Method: This study was multicenter prospective cohorts study that conducted data from 9 university-affiliated
SICUs in Thailand between April 2011 and January 2013. We collected and evaluated data of AMI events. The patients were
followed-up for up to 28 days after admitted to the SICUs.
Results : The overall incidence of AMI in SICU was 1.4% (66 of 4,652 patients). Non-ST elevated MI was the most common
electrocardiography (ECG) presentation (75%). The common clinical sign and symptom of AMI included ECG changes
(53%) and elevation of cardiac enzymes (48.5%). Patients with AMI had significantly higher 28-day mortality rate (28.8%
versus 13.6%, p<0.001) than those with non-MI. The Acute Physiologic and Chronic Health Evaluation (APACHE) II scores
(RR 1.04, 95% CI 1.01-1.07, p = 0.003) and age >65 year (RR 2.54, 95% CI 1.36-4.75, p = 0.003) were significant risk
factors of AMI.
Conclusion : The incidence of AMI in the SICU was uncommon but led to significantly higher mortality rates. The APACHE
II score and age >65 year were significant predictors of AMI in SICU.
Keywords : Acute myocardial infarction, Incidence, Predictors, Outcomes, Surgical intensive care unit.
