The Correlation of Left Ventricular Hypertrophy with the Severity of Atherosclerosis and Embolic Events+
Nattawut Wongpraparut, MD*, Sirin Apiyasawat, MD*, Suraj Maraj, MD*, Larry E Jacobs, MD*, Morris N Kotler, MD*
Affiliation : + This study was presented in XXIII Congress of European Society of Cardiology in Stockholmes, Sweden, September 2, 2001 * Department of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA
Objective : The study was undertaken to assess the correlation between the presence and degree of aortic
atheroma with degree of Left ventricular (LV) mass index and subsequent clinical outcomes.
Materials and Methods : The authors studied the clinical profiles of 87 patients with aortic atherosclerosis
and controls, who had undergone TEE between 1995 and 2000.
Results : Mean LV mass index was 116gram/m2 in atherosclerosis group compared to 81gram/m2 in the
control group (p < 0.009). In the atherosclerotic group, there was a close correlation between LV mass index
score and severity of the plaque in the aortic arch and descending aorta (p < 0.001, 0.001). The presence of
large ulcerated plaque had a significant correlation with stroke (p < 0.002).
Conclusion : 1) LV mass index correlates with the severity of aortic atheroma. 2) Smoking, elevated mean
arterial blood pressure and a high LV mass index score are significantly correlated with large ulcerated
plaque and stroke. 3) These findings may in part explain the higher cardiovascular risk in patients with
increased left ventricular mass.
Keywords : Left ventricular mass index, Aortic atheroma, Stroke, Transesophageal echocardiography
