Serotonin Syndrome: A Case Report
Surachai Likasitwattanakul, MD*
Affiliation : * Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai
Serotonin syndrome is a rare but potentially fatal complication of drugs that have effects on central nervous system serotonin. It is characterized by sudden onset of altered mental status, increased neuromus- cular activity and autonomic instability. The author reports a child with suprasellar region tumor who presented with depression and obsessive-compulsive disorder and received a combination of sertaline (se- lective serotonin reuptake inhibitor) and clomipramine (tricyclic antidepressant). Symptoms of serotonin syndrome occurred within 24 hours after increasing the dose of sertaline. The patient’s symptoms resolved rapidly with discontinuation of the offending drugs and supportive care.
Keywords : Serotonin syndromr, Children
