Predictors of Non-Significant Endoscopic Findings in Patients with Suspected Upper Gastrointestinal Tract Hemorrhage
Preeda Sumritpradit MD*, Suwat Tangkittimasak MD*, Panuwat Lertsithichai MD*
Affiliation : * Department of Surgery, Ramathibodi Hospital and Medical School, Mahidol University
Objectives : The objective of the present study was to determine pre-endoscopic predictive factors of non-
significant endoscopic findings in patients with suspected upper gastrointestinal tract hemorrhage (UGIH).
Materials and Methods : Medical records of 187 patients admitted with the primary diagnosis of UGIH were
reviewed. Non-significant endoscopic findings were defined as “normal”, “mild gastritis” or unspecified
gastritis with a hospital stay of two days or less. Possible predictors of non-significant endoscopic findings
included pertinent history, physical examination, nasogastric tube aspirate, routine laboratory findings, and
units of infused packed red cells (PRC). Multiple logistic regression analysis was used to determine signifi-
cant predictors.
Results : Predictors of non-significant endoscopic findings included the absence of comorbid diseases (OR:
6.4; 95%CI: 3.0-13.6), higher platelet count (OR: 1.7 per 100,000 increase; 95%CI: 1.1-2.5) and less PRC
infusion (OR: 1.9 per unit decrease; 95%CI: 1.3-2.7).
Conclusion : Patients with UGIH who may have a negative EGD can be identified prior to endoscopy.
Keywords : Predictors, Non-significant findings, Endoscopy, Upper gastrointestinal hemorrhage
