Angiomatoid Fibrous Histiocytoma with Pain in a Child
Piriya Sutthiruangwong, MD*, Voranuch Thanakit, MD**, Apichat Assavamongkolkul, MD***
Affiliation : * Department of Pathology, Chonburi Hospital, Chonburi ** Department of Pathology, Faculty of Medicine, Chulalongkorn University *** Department of Orthopaedic Surgery and Rehabilitation, Faculty of Medicine, Siriraj Hospital, Mahidol University
Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor with low-grade malignancy which occurs chiefly in children and young adults. Mostly, the tumor develops in the extremities or the trunk. The tumor has a relatively rare metastasis and its overall clinical outcome is excellent. The authors present a case of AFH of the subcutis on a left elbow of an 11-year-old boy. Clinically, the tumor appears as a cutaneous nodule with slow growth. Pain and adjacent lymphadenopathy are leading symptoms of the patient. Histo- logical examination shows the classical morphological features of AFH with focal cellular atypia. The tumor has immunoreactivity to vimentin and CD68 but negative to CD34, desmin, CD117 and S-100 protein. Because of its rarity, we report a case with an uncommon clinical presentation in a Thai patient.
Keywords : Angiomatoid fibrous histiocytoma, Fibrous histiocytoma, Angiomatoid tumor
