Comparative Study between Preoperative and Postoperative Histologic Grading in Adenocarcinoma of the Colon and Rectum
Bunlue Chaleoykitti MD*
Affiliation : * Division of Colorectal Surgery, Department of Surgery, Phramongkutklao Hospital
Background : Preoperative histologic grading was used to decide the length of the margin of resection in
adenocarcinoma of colon and rectum.
Objectives : The aim of the present study was to determine the accuracy of preoperative histologic grading by
comparison with postoperative histologic grading.
Materials and Methods : Preoperative and postoperative histologic grading of patients with adenocarcinoma
of the colon and rectum in the department of surgery, Phramongkutklao Hospital between January 1999 and
October 2004 were collected and compared together using percentage and chi-square test.
Results : 260 patients were included in the present study. 47.3% of all cases had inaccurate preoperative
histologic grading. 43% of all cases had worse differentiation. 52.7% of all cases had the same differentiation.
Only 4.3% of all cases had better differentiation.
Conclusion : Preoperative histologic grading was not accurate and could not be used in deciding the length
of the margin of resection.
Keywords : Adenocarcinoma, Rectum, Colon, Differentiation, Grading
