Microalbuminuria Prevalence Study (MAPS) in hypertensive Patients with Type 2 Diabetes in Thailand
Peera Buranakitjaroen MD, DPhil*, Chaicharn Deerochanawong MD**, Pongamorn Bunnag MD***
Affiliation : * Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University ** Endocrinology Unit, Department of Medicine, Rajavithi Hospital *** Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Background : Microalbuminuria represents the earliest clinical evidence of diabetic nephropathy, and is a
marker of increased cardiovascular (CV) morbidity and mortality.
Objectives : This analysis of Thai data from the Microalbuminuria Prevalence Study (MAPS) assessed the
prevalence of macroalbuminuria and microalbuminuria in hypertensive patients with type 2 diabetes.
Design : Cross-sectional clinic-based epidemiological study.
Materials and Methods : A total of 100 patients were enrolled, of which 97 patients constituted the per-protocol
population (patients with bacteriuria and haematuria were excluded). Patients attended one study visit with
no follow-up.
Results : Overall, the prevalence of diabetic kidney disease was high, with macroalbuminuria contributing
13.4% [9.9-16.9; 95% confidence interval (CI)] and microalbuminuria contributing 43.3% [38.3-48.3; 95%CI].
Conclusion : Annual screening for microalbuminuria is recommended for all patients with type 2 diabetes, as
early treatment is critical for reducing CV risks. Clinical studies have shown that renin-angiotensin system
inhibitors can slow the progression of diabetic nephropathy.
Keywords : Diabetic nephropathy, Hypertension, Albuminuria, Renin-angiotensin system, Thailand
