The Correlations between Central Corneal Thickness and Age, Gender, Intraocular Pressure and Refractive Error of Aged 12-60 Years Old in Rural Thai Community
Manapon Lekskul MD*, Pote Aimpun MD, DrPH**, Bandit Nawanopparatskul***, Saran Bumrungsawat***, Thosapon Trakulmungkijkarn***, Jiradech Charoenvanichvisit***, Thanun Herunpattarawong***, Panthep Suksangthong***, Teerapat Jaiprasat***, Monsit Rattananantapat***, Trin Sudprasert***
Affiliation : *Department of Ophthalmology, Phramongkutklao Hospital, **Department of Military and Community Medicine, Phramongkutklao College of Medicine, *** Phramongkutklao College of Medicine
Objectives : To study the normal Central Corneal Thickness (CCT) and investigate the correlation between
CCT and age, gender, intraocular pressure and refractive error.
Materials and Methods : Population of age 12-60 years old were interviewed with standard questionnaire.
Refractive error was measured and graded according to spherical equivalent power. Then intraocular pressure
and central cornea thickness were measured by applanation tonometer and ultrasonic pachymeter, respec-
tively. The data were analyzed using T-test, correlation and multivariate linear regression to identify mean CCT
and correlation between age, gender, intraocular pressure, and refractive error.
Results : A total of 467 participants were enrolled into the study. One hundred and eighty-six (39.8%) were
males and 281 (60.2%) were females. The average CCT was 535.2±29.9 µm. The mean CCT of right and
left eyes were 535.3±30.4 µm, and 535.1±29.5 µm, respectively. The multivariate linear regression
indicated that increasing in age would decrease the CCT 0.28 µm and an increasing of intraocular pressure
would increase the CCT 1.4 µm statistically significance.
Conclusion : The CCT was independently related to the refractive error and gender. Greater CCT was associ-
ated with higher intraocular pressure. Conversely, thinner cornea was correlated with older age group.
Keywords : CCT, Intraocular pressure, Refractive error, Age, Gender
