Intraperitoneal Lidocaine for Decreasing Intra-Operative Pain during Postpartum Tubal Resection in Srinagarind Hospital
Duangporn Rattanalappaiboon MD*, Yuthapong Werawatakul MD*, Piangjit Tharnprisan RN**, Molruedee Prasit RN**
Affiliation : * Department of Obstetrics and Gynecology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand ** Family Planning Unit, Nursing Division, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand
Objective : To evaluate the effectiveness and determine the minimal dosage of intraperitoneal lidocaine for pain relief during
postpartum tubal resection in Srinagarind Hospital.
Material and Method: Sixty postpartum women, undergoing postpartum tubal resection performed by residents at the
Department of obstetrics and gynecologic, were included in this randomized, double-blinded, placebo controlled study. They
were randomly assigned to one of three groups. They all received 20 ml solution intraperitoneally. Group one received it as
isotonic normal saline; group 2 received it with 100 mg of lidocaine; and group 3 received it with 200 mg of lidocaine. The
intra-operative and post-operative pain was measured by using a numerical rating score (NRS, from 0-10).
Results : The mean of intra-operative NRS in the lidocaine groups (100 and 200 mg) were significantly lower than the isotonic
normal saline group (3.40, 3.50 vs. 6.55, p-value 0.019 and 0.024). No significant difference was found in the intra-operative
NRS between 100 and 200 mg lidocaine (NRS 3.40 vs. 3.50, respectively, mean difference 95% CI -2.41 to 2.21). There was
no significant difference in the immediate post-operative pain among these three groups (p-value 0.613).
Conclusion : Intraperitoneal lidocaine instillation provides effective intra-operative pain relief in postpartum tubal resection
under local anesthesia. 100 mg of lidocaine is effective in pain relief. This technique was not effective for relief of immediate
post-operative pain.
Keywords : Intraperitoneal lidocaine, Postpartum tubal resection, Pain control, Srinagarind Hospital
