Validate of Clinical Risk Index for Osteoporosis in Thai Women at Phramongkutklao Hospital
Ekachai Leeangkoonsathian MD*, Pongrak Boonyanuruk MD*, Chatlert Pongchaiyakul MD**, Suthee Panichkul MD***
Affiliation : * Department of Obstetrics and Gynecology, Phramongkutklao Hospital, Bangkok, Thailand ** Division of Endocrinology and Metabolism, Department of Medicine,Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand *** Department of Obstetrics and Gynecology, Phramongkutklao College of Medicine, Bangkok, Thailand
Background..: Osteoporosis is a common problem found in elderly people and the cost of treatment with its complications is
much higher than the cost of diagnosis and prevention. However, diagnosis of osteoporosis is hindered by an unavailability
of dual energy x-ray absorptiometry (DXA). Many clinical risk index-scoring systems were developed to help prediction of
osteoporosis such as Khon Kaen Osteoporosis Study (KKOS). The KKOS is one among those scoring systems based on the
Thai population database. The objectives of the present study were to validate KKOS for prediction of osteoporosis in Thai
women at Gynecologic Clinic of Phramongkutklao Hospital and to study the prevalence of women with osteoporosis
diagnosed with KKOS.
Material and Method: Four hundred forty six Thai women, aged 40 years or more attending the Gynecologic Clinic of
Phramongkutklao Hospital, and had Bone mineral density (BMD) result were enrolled in the present study. The results of
BMD were measured at the lumbar spine and femoral neck by DXA and KKOS. The score was evaluated and compared.
Results : Sensitivity and specificity of KKOS for prediction of osteoporosis were 48.6% and 68.1%, respectively. Prevalence
of osteoporosis using KKOS was 23% while 32% were diagnosed with DXA.
Conclusion : KKOS had low sensitivity and specificity for diagnosed osteoporosis in Thai women at Gynecologic Clinic of
Phramongkutklao Hospital.
Keywords : Osteoporosis, Clinical risk scoring system, KKOS
