Isolated Corneal Intraepithelial Neoplasia
Orasa Horatanaruang MD*, Orathai Chansanti MD*, Winyou Mitarnun MD**, Kobkul Tungsinmunkong MD**
Affiliation : * Department of Ophthalmology, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Hat Yai, Songkhla ** Department of Pathology, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Hat Yai, Songkhla
Objectives : To report two cases of isolated corneal intraepithelial neoplasia.
Materials and Methods : The present study included 2 cases presenting with isolated corneal intraepithelial
neoplasia. Both patients were treated by corneal epithelial scraping.
Results : The authors present the clinical picture and histopathological findings of 2 patients suffering from
corneal intraepithelial neoplasia that did not arise from the corneoscleral limbus. Both patients showed no
recurrence after treatment for a period of time.
Conclusion : Isolated corneal intraepithelial neoplasia is rare. Corneal scraping may be an effective treatment.
Keywords : Corneal intraepithelial neoplasia, Carcinoma in situ, Squamous cell carcinoma
