Preoperative Vaginal Preparations for Abdominal Hysterectomy for the Prevention of Febrile Morbidity: Savlon Douching vs Povidone-iodine Painting
Kullathida Sowapat MD*, Sukree Soontrapa MD*, Chuanchom Sakondhavat MD*
Affiliation : * Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen
Objective : To compare the effectiveness between savlon solution was douching and povidone-iodine solution
painting for reducing febrile morbidity after total abdominal hysterectomy.
Study
Design : Clinical trial.
Materials and Methods : One hundred and fifty patients at Srinagarind Hospital were scheduled for total
abdominal hysterectomy (TAH). All subjects were non-randomly allocated to receive either savlon (1:1000
solutions) douching or povidone-iodine (1% solution) painting as pre-operative vaginal preparations. They
also received Cefazolin 1 gm. intravenously before the operation. The principal outcome of the study was
febrile morbidity.
Results : The overall rate of febrile morbidity was 21 percent. The incidence of febrile morbidity in the savlon
vs. povidone-iodine groups was 16 (12/75) and 25 (19/75) percent, respectively. No statistically significant
difference was found between the two groups (p-value = 0.16). The odds ratio was 1.78 (95%CI 0.79 to 3.99)
and adjusted odds ratio was 2.09(95%CI 0.86 to 5.10)
Conclusion : The effectiveness between savlon solution douching and povidone-iodine solution painting in
conjunction with a prophylactic antibiotic before TAH for reducing febrile morbidity was not significant
different.
Keywords : Vaginal preparation, Total abdominal hysterectomy, Febrile morbidity
