Survival Rate of Recurrent Cervical Cancer Patients
Sukkasam Poolkerd MD*, Surawut Leelahakorn MD*, Sumonmal Manusirivithaya MD*, Siriwan Tangjitgamol MD*, Taovalai Thavaramara MD*, Pacheun Sukwattana MD*, Kamol Pataradule MD*
Affiliation : *Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration Medical College and Vajira Hospital
Objectives : To determine the survival rate of recurrent cervical cancer patients and factors influencing survival
Materials and Methods : The subjects were identified from the Gynecologic Oncology Unit tumor registry
record. The pathological, clinical data including the follow-up information of recurrent cervical cancer
patients who were treated in the Gynecologic Oncology Unit, Bangkok Metropolitan Administration Medical
College and Vajira Hospital between 1992 and 2003 were retrospective reviewed.
Results : During the study period, 144 recurrent cervical cancer patients were identified. Mean age of the
patients was 52 years. The median time from complete primary treatment to disease recurrence was 14.8
months. Seventy-two patients (50%) had previous stage III disease. The most common histopalogy was squa-
mous cell carcinoma (72.9%). Approximately half of the recurrences were local (73 patients or 50.7%) and
distal recurrences were encountered in 71 patients or 49.3%. Overall 109 patients received treatment for their
recurrences, i.e. radiation alone (55 patients, 38.2%), chemotherapy (31 patients, 21.5%), chemotherapy and
radiation (18 patients, 12.5%), surgery (5 patients, 3.5%), and 35 patients (24.3%) received only supportive
treatment. Two-year survival rate of the group was 18.5%. Median survival was 8 months (95%CI, 7-10
months). The patients with only local recurrence had a 2-year survival rate of 22.2% compared to 14.6% in
those with distant recurrence. (p = 0.245). Two-year survival rate of those who received any kind of treatment
was 22.4% compared to 4.0% in those who received only supportive treatment (p = 0.014 and 0.017 in
univariable and multivariable analysis respectively).
Conclusion : Survival rate of recurrent cervical cancer was low, especially in those who received only support-
ive treatment.
Keywords : Recurrent cervical cancer, Survival rate
