Naesinee Chaiear MD, M Med Sc, PhD*, Bangornsri Jindawong BSc*, Watchara Boonsawas MD, PhD**, Tipaporn Kanchanarach MSc***, Pornpun Sakunkoo MSc****
Affiliation : * Units of Occupational Medicine, Community Medicine Department, Health, Khon Kaen University, Khon Kaen ** Respiratory and Critical Care Medicine, Internal Medicine Department, Health, Khon Kaen University, Khon Kaen *** Community Pharmacy Department, Faculty of Pharmaceutical Science, Health, Khon Kaen University, Khon Kaen **** Department of Environment Science, Faculty of Public Health, Khon Kaen University, Khon Kaen
Background : According to studies from different countries, the prevalence of natural rubber latex (NRL)
sensitization in healthcare workers ranges from 2.9 to 17%. The incidence and prevalence of sensitization and
allergy to NRL in Thailand is limited to two studies. There is no study among the high risk healthcare workers.
Objectives : 1) To estimate the prevalence of natural rubber latex (NRL) glove allergy and NRL sensitization
among nurses; 2) To describe its clinical symptoms.
Materials and Methods : Included in the present study were 412 nursing and medical record staff. A self-
administered questionnaire was used to collect personal biodata and individual allergy histories to NRL
products. Skin prick tests (SPTs) with the commercial NRL allergens; Stallerg(cid:31)nes, S.A, Fresnes, France, and
common environmental allergens, were performed.
Results : The questionnaire response rate was 88% (412/470), 93% females. The response rate of SPT was 72%
(295/412) (95%CI 67.2, 76.0). The prevalence of NRL glove allergic symptoms and NRL sensitization was
24% (95%CI 19.9, 28.1) and 2% (95%CI 0.4, 3.6), respectively. The most frequently reported symptoms among
the positive SPT to NRL was angioedema. Five of the six NRL sensitised subjects had had high exposure to
NRL.
Conclusion : NRL sensitization among Thai nursing staff is less prevalent than in healthcare workers in
Europe.
Keywords : Natural rubber latex, Latex, Allergy, Nurses, Sensitization, Healthcare worker
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