Myasthenia Gravis Accompanied with Hypokalemic Periodic Paralysis
Kittisak Sawanyawisuth MD*, Somsak Tiamkao MD*, Thongchai Pratipanawatr MD*
Affiliation : * Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen
Myasthenia gravis and hypokalemic periodic paralysis are commonly related with hyperthyroidism but rarely occur together. Here, the authors reported a case of hypokalemic periodic paralysis in a Northeast- ern Thai woman accompanied with myasthenia gravis. She had motor weakness despite a normal level of serum potassium. Prostigmine test was positive. She dramatically improved after pyridostigmine treatment. Autoantibodies to nicotinic AchR-Ab and dihydropyridine receptor or L-type voltage gated calcium channel were postulated to explain these associated diseases.
Keywords : Myasthenia gravis, Hypokalemia, Periodic paralysis
