Bacteriology of Granulation Tissue in Laryngotracheal Stenosis Patients
Wisoot Reechaipichitkul MD*, Surasakdi Wongratanacheewin PhD**, Teeraporn Ratanaanekchai MD*, Surapol Suetrong MD*, Suwanna Nonthapa BsC**
Affiliation : * Department of Otolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen ** Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen
Background : The formation of granulation tissue is an important factor promoting recurrence after surgical
treatment of laryngotracheal stenosis. Bacterial infection was claimed to be the cause.
Objective : The present study aimed to identify the bacteriology of granulation tissue in laryngotracheal
stenosis patients.
Materials and Methods : Data was collected prospectively. Granulation tissue found in the site of laryngotra-
cheal stenosis was removed and sent to the microbiologic study to identify the organisms.
Results : Twenty-four specimens from 17 patients were included in the present study. Coagulase-positive
Staphylococcus (45.8%) was the most common gram-positive organism and Pseudomonas aeruginosa as well
as Enterobacter species (16.7%) were the most common gram-negative bacteria. Ciprofloxacin may be the
oral antibiotic that should be recommended.
Conclusion : Coagulase-positive Staphylococcus, Pseudomonas aeruginosa as well as Enterobacter species
were the common organisms identified from the granulation tissue in recurrent laryngotracheal stenosis. Oral
antibiotics, such as ciprofloxacin, may have benefit in reducing the formation of this granulation tissue.
Keywords : Laryngotracheal stenosis, Granulation tissue, Bacteriology
