The Clinicopathology and Outcome of Post-Infectious Glomerulonephritis: Experience in 36 Adults
Nattachai Srisawat MD*, Laor Aroonpoonsub MD*, Songkiat Lewsuwan MD*, Talengsak Kanjanabuch MD*, Yingyos Avihingsanon MD*, Kearkiat Praditpornsilpa MD*, Kraing Tungsanga MD*, Sawaluk Chusil MD*, Somchai Eiam-ong MD*
Affiliation : * Department of Medicine, Department of Pathology, Faculty of Medicine, Chulalongkorn University Hospital
Post-infectious glomerulonephritis is one of the most common causes of acute glomerulonephritis. A retrospective study of post-infectious glomerulonephritis at King Chulalongkorn Memorial Hospital, Thailand was performed from January 1999 to December 2005. Among thirty six patients, eight cases were post- streptococcal glomerulonephritis and twenty eight cases were post non-streptococcal Glomerulo Nephritis (GN). Most cases present with edema, hypertension, gross hematuria and nephrotic-range proteinuria. C3 and CH50 commonly were low. Post-streptococcal glomerulonephritis had more aggressive pathology compared to the others. However, the long term outcome was excellent. In the present study the authors found ESRD in only 14.3% (4 out of 28 cases) that reflects the excellent prognosis of post-infectious glomerulo- nephritis. Of interest, all of the ESRD patients were caused by post non-Streptococcal GN. Even though, no statistic was achieved; it might reflect the aggressiveness of non-Streptococcal pathogen.
Keywords : Post-infectious Glomerulonephritis, Post-streptococcal Glomerulonephritis, Outcome
