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Health Check-Up Program for Pre/Postmenopausal Women at Siriraj Menopause Clinic

Surasak Angsuwathana MD*, Pichai Leerasiri MD*, Manee Rattanachaiyanont MD*, Prasong Tanmahasamut MD*, Chongdee Dangrat MSc*, Suchada Indhavivadhana MD*, Kitirat Techatrisak MD*

Affiliation : * Gynecologic Endocrinology Unit, Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University

Objective : To determine the general health status of pre/postmenopausal women attending the menopause clinic. Study
Design : Retrospective descriptive study.
Setting : Siriraj Menopause Clinic, Gynecologic Endocrinology Unit, Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University. Study population: Pre/postmenopausal women (i) presumed to have no medical disease (no disease group) or (ii) with unknown status of medical disease (no record group) and undergoing health check-up program at the time of registration without prior hormone therapy.
Materials and Methods : Medical records of new patients registering at the menopause clinic from January 1999 to December 2005 were reviewed.
Results : Among 1,020 patients undergoing health check-up program, there were 366 patients in the no disease group. They had abnormal health parameters listing by frequency of prevalence including hypercho- lesterolemia (62.3%), suboptimal blood pressure (49.3%), overweight to obese (30.2%), suboptimal fasting blood sugar (27.9%), hypertriglyceridemia (21.3%), abnormal liver function tests (5.4-6.9%), and abnormal kidney function tests (0.5%). The prevalence of dyslipidemia was statistically higher in the no record group compared to the no disease group; such abnormal parameters included hypercholesterolemia (>200 ml/dL), high blood level of low density lipoprotein cholesterol (LDL-C >130 mg/dL), and high ratio between LDL-C and high density lipoprotein cholesterol (LDL-C/HDL-C ratio >3). Osteoporosis was found in 6.6% of the patients. Abnormal mammographic findings that needed close follow-up or breast biopsy were found in 13.5%. Twelve patients had breast biopsy and none had breast cancer.
Conclusion : Abnormal health parameters are common in pre/postmenopausal women presumed to have no medical disease. The similar or even worse findings are also found in those whose status of medical diseases was unknown. Therefore, a routine health screening program, especially for metabolic diseases, should be offered to pre/postmenopausal women regardless of their medical history.

Keywords : Health, Check-up, Menopause


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