Inhaled Iloprost for Severe Persistent Pulmonary Hypertension of the Newborn
Uraiwan Chotigeat MD*, Santiwan Jaratwashirakul MD*
Affiliation : * Neonatal Unit, Department of Pediatrics, Queen Sirikit National Institute of Child Health
The authors report one case of persistent pulmonary hypertension that had hypoxia although receiv- ing treatment with high frequency oscillation, inotropic drugs, blood transfusion, and oral sildenafil for pulmonary vasodilatation. The patient developed hypotension after two doses of oral sildenafil and no re- sponse to high dose of inotropic drugs. So aerosolized iloprost was given via endotracheal tube and oxygen saturation improved within 10 minutes. Oxygen was weaned at 36 hours after treatment with this drug and no any side effect was found.
Keywords : Iloprost, PPHN, Sildenafil
