A Comparison of Three Organ Dysfunction Scores: MODS, SOFA and LOD for Predicting ICU Mortality in Critically Ill Patients
Bodin Khwannimit MD*
Affiliation : * Division of Critical Care, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla
Objective : To compare the validity of the Multiple Organ Dysfunction Score (MODS), Sequential Organ
Failure Assessment (SOFA), and Logistic Organ Dysfunction Score (LOD) for predicting ICU mortality of Thai
critically ill patients.
Materials and Methods : A retrospective study was made of prospective data collected between the 1st July 2004
and 31st March 2006 at Songklanagarind Hospital.
Results : One thousand seven hundred and eighty two patients were enrolled in the present study. Two hundred
and ninety three (16.4%) deaths were recorded in the ICU. The areas under the Receiver Operating Curves
(AUC) for the prediction of ICU mortality the results were 0.861 for MODS, 0.879 for SOFA and 0.880 for LOD.
The AUC of SOFA and LOD showed a statistical significance higher than the MODS score (p = 0.014 and
p = 0.042, respectively). Of all the models, the neurological failure score showed the best correlation with
ICU mortality.
Conclusion : All three organ dysfunction scores satisfactorily predicted ICU mortality. The LOD and neuro-
logical failure had the best correlation with ICU outcome.
Keywords : Multiple organ dysfunction, Organ failure, Intensive care unit, Critically ill, Mortality
