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Indomethacin for Recurrent Cutaneous Necrotizing Eosinophilic Vasculitis

Chuchai Tanglertsampan MD*, Niyom Tantikun MD*, Nopadon Noppakun MD**, Virat Pinyopornpanit MD***

Affiliation : * Skin Center, Bumrungrad International **Division of Dermatology, Department of Medicine, Faculty of Medicine, Chulalongkorn University *** Division of Rheumatology, Department of Medicine, Bumrungrad International Hospital

Recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) is a rare disease characterized by clinical features of pruritic purpuric papules and angioedema. Skin biopsies revealed the eosinophil-pre- dominate necrotizing vasculitis affecting small dermal vessels. Systemic corticosteroid is a very effective treatment. There are many side effects associated with systemic corticosteroid therapy. The authors report a case of RCNEV successfully treated with indomethacin. To the authors’ knowledge, there has been no reported case of RCNEV treated with indomethacin.

Keywords : Indomethacin, Recurrent cutaneous necrotizing eosinophilic vasculitis, Treatment


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