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Paraphayngeal Salivary Duct Carcinoma Involving the Cavernous Sinus

Noppadol Larbcharoensub MD*, Juvady Leopairut MD*, Jumroon Tungkeeratichai MD**, Jiraporn Laothamatas MD***

Affiliation : * Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University ** Department of Otolaryngology, Faculty of Medicine Ramathibodi Hospital, Mahidol University *** Department of Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University

Salivary duct carcinoma (SDC) is a relatively uncommon malignant tumor of the salivary gland derived from the excretory duct reserve cells of the salivary glands. The authors report a case of SDC in a 34- year-old man who presented with trismus and left sided headache, radiologically by a left parapharyngeal mass involving into the left cavernous sinus and histologically by intraductal growth pattern with a cribri- form appearance and comedonecrosis. Perineural invasion of the mandibular branch of trigeminal nerve is demonstrated. Clinical and pathologic features with relevant literatures are reviewed.

Keywords : Salivary duct carcinoma, Parapharynx, Cavernous sinus


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