Psychometric Properties of WHOQOL-BREF-THAI in Patients with HIV/AIDS
Phantipa Sakthong PhD*, Jon C Schommer PhD**, Cynthia R Gross PhD***, Rungpetch Sakulbumrungsil PhD****, Wisit Prasithsirikul MD*****
Affiliation : * Faculty of Pharmaceutical Sciences, Chulalongkorn University, Thailand ** College of Pharmacy, University of Minnesota, USA *** College of Pharmacy and School of Nursing, University of Minnesota, USA **** Faculty of Pharmaceutical Sciences, Chulalongkorn University, Thailand ***** Bamrasnaradura Infectious Disease Institute, Thailand
Objective : To assess reliability and validity of the Thai abbreviated version of World Health Organization
quality of life (WHOQOL-BREF-THAI) in HIV/AIDS patients.
Materials and Methods : The present study is descriptive research. Data were purposively collected from 120
HIV/AIDS outpatients at Bamrasnaradura Infectious Disease Institute, Thailand, during September-December,
2004.
Results : Cronbach’s alpha ranged from 0.61 to 0.81 across domains. Exploratory factor analysis identified
four major domains: physical, psychological, social and environmental domains, corresponding to the four
WHOQOL-BREF domains. The four domain scores correlated positively with general health satisfaction and
overall quality of life questions (all p < 0.01 except general health & social domain p < 0.05), and correlated
negatively with the frequency and severity of HIV symptoms (all p < 0.01). The four domain scores discriminated
between patients with higher and lower frequency and severity of HIV symptoms (all p < 0.01).
Conclusion : The present study shows that WHOQOL-BREF THAI can be a good generic health-related quality
of life instrument in HIV/AIDS patients.
Keywords : Health-related quality of life, WHOQOL-BREF-THAI, Validity, Reliability, HIV/AIDS
