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Bisphosphonate-Related Osteonecrosis of the Jaws (ONJ): A Report of Two Cases

Chatlert Pongchaiyakul MD*, Krittinant Auraiwan DDS**, Praew Kotruchin MD*, Churairat Kularbkaew MD***

Affiliation : * Department of Medicine, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen ** Division of Oral Maxillofacial Surgery, Dental Department, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen *** Department of Pathology, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen

Osteonecrosis of the jaw (ONJ) is strongly associated with the use of aminobisphosphonates. Herein, the authors report two cases of ONJ after intravenous bisphosphonate therapy including clinical presenta- tions, X-ray, and pathological findings. Since there is no definite treatment for ONJ, the focus should be on prevention with a dental evaluation for all patients before starting bisphosphonates.

Keywords : Osteonecrosis of the jaw, Bisphosphonate, Thailand


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