Cryptococcal Meningoradiculitis: An Atypical Presentation after Initiation of Antiretroviral Therapy
Ubonvan Jongwutiwes MD*, Kumthorn Malathum MD**, Somnuek Sungkanuparph MD**
Affiliation : * Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok **Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok
Atypical presentations of cryptococcal infection have been described as clinical manifestations of immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients following commence of antiretroviral therapy (ART). The authors describe a patient presenting with cryptococcal meningoradiculitis two weeks after initiation of ART. In patients with advanced HIV disease, immune reconstitution induced by ART can precipitate onset of atypical clinical manifestations in those patients with latent cryptococcal infection of the central nervous system.
Keywords : Cryptococcus, Meningoradiculitis, HIV, Immune reconstitution inflammatory syndrome
