Extragonadal Germ Cell Tumor of Oesophagus in a Young Female Patient: A Case Report
Warunporn Siriboonpipattana, MD1, Kosin Wirasorn, MD1, Piyakarn Watcharenwong, MD1, Thanakorn Charoenthanadhol, MD1, Siraphong Putraveephong, MD1, Nipon Chaisuriya, MD2, Jarin Chindaprasirt, MD1
Affiliation : 1Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, 2Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Background: This case report describes an exceptionally rare instance of a mixed germ cell tumor located in the esophagus of a young female patient.
Case Report: A 21-year-old woman without a family history of cancer presented with dysphagia and hepatomegaly. Histopathological and immunohistochemical findings of the esophageal mass were consistent with a mixed germ cell tumor, predominantly yolk sac tumor with minor choriocarcinoma-like differentiation. Despite extensive liver metastasis, the patient responded well to a modified BEP chemotherapy regimen.
Conclusion: This case highlights the aggressive nature of extragonadal germ cell tumors and the importance of the correct diagnosis and prompt initiation of chemotherapy.
Keywords : Extragonadal germ cell tumor; Esophagus; Mixed germ cell tumor; Yolk sac tumor; Chemotherapy; BEP regimen; Rare malignancy
