Ovarian Reserve Evaluation by Anti-Mullerian Hormone in Women Undergoing Laparoscopic Cystectomy of Endometrioma
Singpetch Suksompong MD*, Surachai Dejarkom MD*, Somsin Petyim MD*, Chongdee Dangrat MSc**, Daunpen Orachon BNS*, Roungsin Choavaratana MD*
Affiliation : * Infertility Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ** Gynecologic Endocrinology Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Objective : To study the serial changes of serum AMH to determine ovarian reserve recovery after laparoscopic cystectomy
of endometrioma.
Material and Method: Forty-three endometrioma patients who underwent laparoscopic cystectomy of endometrioma were
tested for levels of serum AMH at preoperation, 1 week, and 3 months postoperation.
Results : Median serum AMH was 2.11 ng/mL (range = 0.22 to 9.24 ng/mL) before surgery. This level also reduced at
first week postoperation (p < 0.01) but did not reach a significant difference between the first week and the third month
(1.02 ng/mL and 1.06 ng/mL, respectively). The recovery rate of AMH level in unilateral endometrioma was higher than
bilateral endometrioma (32.4% vs. -3.6%, p = 0.02).
Conclusion : Ovarian reserve was decreased after laparoscopic cystectomy of endometrioma and did not significantly restore
after three months of postoperation. The recovery of ovarian reserve after unilateral endometriotic cystectomy was faster
than that after bilateral endometriotic cystectomy.
Keywords : Ovarian reserve, Anti-mullerian hormone, Endometrioma, Laparoscopic cystectomy
