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Risk Factors of Ectopic Pregnancy

SUVIT BUNY AV EJCHEVIN, MD, MHS*, PIYALUMPORN HA VA NOND, MS**, WIRACH WISA WASUKMONGCHOL, MD*

Affiliation : *Department of Obstetrics and Gynecology, Faculty of Medicine, ** Institute of Health Research, Chulalongkom University, Bangkok 10330, Thailand.

Abstract

Objectives : To assess the risk factors of ectopic pregnancy in Thai women.
Setting : Department of Obstetrics and Gynaecology, Faculty of Medicine, Chulalongkom University.
Design : Case controlled study.
Materials and Methods : From 1999 to 2000, 208 cases of ectopic pregnancy and 781 controls (postpartum women) were included in the study. The women were interviewed by trained research interviewers using a standardized questionnaire. Detailed information regarding age at first intercourse, number of sexual partners, history of changing partners within 6 months, previous obstetric history, history of spontaneous and criminal abortion, history of pelvic inflammatory disease, smoking, history of endometriosis and history of previous ectopic pregnancy was collected.
Results :By multivariate analysis, 5 variables remained as strong and independent risk fac tors for ectopic pregnancy : the number of sexual partners~ 2 (OR= 3.02, 95% CI (1.75-5.23), vaginal delivery~ 1 (OR= 0.005, 95% CI (0.002-0.0015), history of pelvic inflamatory disease (OR= 3.17, 95% CI (1.40-7.19), smoking (OR= 2.49, 95% CI (1.36-4.55), infertility (OR= 2.74, 95% CI (1.35- 5.54)).
Conclusion : Problems of multiple sexual partners, pelvic inflammatory disease, smoking and infertility were the main risk factors of ectopic pregnancy in Thai women.

Keywords : Risk Factors, Ectopic Pregnancy


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