Airway Complications in Neonates Who Received Mecha
nical Ventilation
THRATHIP KOLAT AT, M.D.*,
KITTIRAT AUNGANON,M.D.**,
PAT CHARIN YOSTHIEM, R.N.***
Affiliation : * Department of Pediatrics,
** Department of Otolaryngology,
*** Pediatric Nursing Section, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
AbstractObjective : To determine the incidence, type and severity of airway complications in high
risk neonates who received conventional mechanical ventilation.
Method : Forty-five infants who had received conventional mechanical ventilation in the
Neonatal Intensive Care Unit, Department of Pediatrics, Faculty of Medicine Siriraj Hospital for at
least 4 days were enrolled. Orotracheal intubation with blue line, non-cuffed, non-shouldered poly
vinylchloride tube was used exclusively. The average number of intubations was 2 (range 1-7), and
the average duration for intubation was 25 days. The details of the intubation, and the presence of
respiratory distress after extubation were recorded. All of the infants had endoscopic examination of
the airway within 5 days of extubation.
Results : Following extubation, 14 (31.1 %) infants developed signs of upper airway obstruc
tion, of which inspiratory dyspnea was the most common manifestation. Only 4 infants developed
inspiratory stridor, three of them had a birth weight greater than 2,500 g. Abnormal bronchoscopic
findings were found in 42 infants, 68.8 per cent had multiple sites of injury. Supraglottic lesions
were found in 55.7 per cent of cases. Laryngomalacia was an associated finding in 8 and gastro
esophageal reflux (GER) in I occasion.
Conclusions : From the result of this study, the authors found that airway complications
related to endotracheal intubation are common among survivors from the Neonatal Intensive Care
Unit. When the diagnosis of airway complications only depends on symptoms and signs of upper
airway obstruction, the incidence and extent of injuries may be under-estimated. When attempted
extubation fails or when VLBW infants develop increasing respiratory distress that is not clearly
explained by an apparent disorder involving the pulmonary parenchyma, flexible bronchoscopic
examination should be performed at the bedside with minimal risk.
Keywords : Airway Complications, Mechanical Ventilation, Endotracheal Intubation, Neonate
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