Background: Having a child with cancer is a crisis for parents. In Vietnam, study examining the psychological problem of mothers having children with cancer is limited.
Objective: To determine level of fatigue in mothers of children with cancer undergoing chemotherapy and some factors related to fatigue of mothers.
Materials and Methods: A cross-sectional study was conducted in 185 mothers of cancer children undergoing chemotherapy at the Ho Chi Minh City Oncology Hospital from February 2018 to May 2018. Using the questionaire to colect data.
Results: The mean age of the mothers was 33.7+6.6 years. The average sleep time was 4.9+1.4 hours/day. 64.3% mothers had moderate fatigue, and 35.7% had severe fatigue. Marital status and average sleep per day, stress and social support were factors related to fatigue of mothers. However, age of mother was not related to fatigue of mothers.
Conclusion: 100% mothers had moderate to high level of fatigue. Therefore, nurses have to aware this issue to assess and provide support to them.

Keywords: Fatigue, Mothers, Childhood cancer, Social support, Stress