J Med Assoc Thai 2010; 93 (1):11

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Evaluation of the Firebird Sirololimus Eluting Stent In All Comers with Coronary Artery Stenosis
Tresukosol D Mail, Pornratanarangsi S , Chotinaiwattarakul C , Tungsubutra W , Phankingthongkum R , Wongpraparut N , Lirdwilai T , Dapang T , Panchavinnin P

Objective: Percutaneous coronary intervention (PCI) has been widely used to treat obstructive coronary
artery disease. With the advent of drug-eluting stent (DES) in real world registry was proved as promising
therapy. The limitation of the use of DES is the limited health care expenditure. We propose the use of Chinese
made DES among Thai patients and that this will solve the cost issue. The clinical result of this DES has not
been well known.

Methods: Prospective study from November 2005 to March 2007 using the structured registry form to evaluate
the safety and efficacy of new Chinese made Firebird sirolimus eluting stent (Firebird SES) on clinical
parameters from in-hospital, 30 days and 12 months or longer term follow-up. End point is major adverse
cardiac event (MACE) including death, MI, TLR and CABG at 30 day and cumulative MACE at 12 month
follow-up.

Results: Ninety consecutive patients who were treated with Firebird stent implantation (107 target lesions)
were analyzed. Angiographic success (defined as < 30% diameter stenosis) was 85%. Procedure success was
77.8%. MACE at 30 day was 16.6%, cumulative MACE at 12 months was 18.8%. There were total 9 deaths
during the study period, two deaths occurred at before 30 days, 3 deaths occurred before 12 months and other
4 deaths occurred after 12 months to 1305 days. Eighty patients (88.9%) had either office visit or telephone
call follow-up after 12 months, 38 patients (42.2%) underwent clinical driven coronary arteriography, binary
restenosis was 26.3%. Shock and smoking history was the analyzed predictor of MACE at follow-up.

Conclusion: The implantation of Firebird DES in unselected patients (all comers) is safe, effective and could
be an alternative choice of stent for Thai patients.

Keywords: Registry, Firebird, sirolimus, drug-eluting stent (DES), outcomes, survival

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