J Med Assoc Thai 2007; 90 (1):179

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Fatal Fulminant Hepatitis Associated with Ganoderma lucidum (Lingzhi) Mushroom Powder
Wanmuang H Mail, Leopairut J , Kositchaiwat C , Wananukul W , Bunyaratvej S

          Hepatotoxic effect related to Ganoderma lucidum (Lingzhi) mushroom powder was first described in a patient from Hong Kong in 2004. In 2005, the authors experienced a case of fatal fulminant hepatitis associated with such a preparation. Both patients had taken other therapeutic agents and traditionally boiled Lingzhi without any toxic effect. After switching to taking Lingzhi in powder form for 1-2 months, the hepatotoxic episode occurred in both patients. The toxic role of Lingzhi powder needs close monitoring in the future, especially in combination with other drugs.

Keywords: Toxic hepatitis, Ganoderma lucidum, Lingzhi powder

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